Upcoming CACA joint webinar with Sciex:


In this webinar, you will learn:

  • Why you need intact protein quantification in biologics discovery and development
  • How to get sensitive, accurate and reliable intact protein quantification results
  • What you can learn from intact protein quantification results

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Unraveling the Structure of a Monoclonal Antibody

Join us for a webinar on Jul 27, 2016 at 1:00 PM EDT.

Register now!

Barry E Boyes


Barry E. Boyes, Ph.D.

Director of Bioscience Products
Advanced Materials Technology, Inc.

In this seminar, the focus will be on the HPLC / UHPLC characterization of biomolecules including: proteins, peptides, and glycosylation variants from a monoclonal antibody. A full review of a top-down and bottom-up approach to the analysis of trastuzumab will be explored.

This presentation will demonstrate how ultrahigh resolution LC-MS analysis of complex biomolecule mixtures can be achieved using conditions that permit excellent separations and analysis, including the use of new fused-core HPLC and UHPLC columns specifically designed for protein analysis. In addition, the consideration of novel mobile phase selection and conditions that favor high performance mass spectral analyses will also be discussed.

Specifically, we will discuss:

• Top-down and bottom-up reversed-phase LC–MS separations of trastuzumab
• The use of new fused-core HPLC and UHPLC columns designed for bio separations.
• Novel mobile phase selection for LC–MS analysis of monoclonal antibodies
• Separations for the analysis of glycosylation variants of monoclonal antibodies

Key Learning Objectives:

• How to characterize a monoclonal antibody with reversed-phase LC–MS and LC-UV separations
• How to utilize novel mobile phase conditions for improved mass spectral analysis of bio-separations
• Learn an optimized workflow for sample work-up and separation of glycosylation variants of monoclonal antibodies

Who Should Attend:

• Method developers for UHPLC and HPLC methods in biotech, biopharma, core laboratories and university research laboratories
• Method developers analyzing large biomolecules
• Method developers analyzing glycans or glycosylation variants of monoclonal antibodies
After registering, you will receive a confirmation email containing information about joining the webinar.


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Call for Nominations for CACA Young Investigator Award

The Chinese American Chromatography Association (CACA) invites nominations for a 2016 CACA Young Investigator Award. The Award recognizes outstanding contributions to the development of separation science and its applications, especially in the field of chromatography. The Award will be presented at the Pittcon Conference & Expo 2016 to be held in March 6 – 10, 2016, in Atlanta, GA, USA. The awardee will give a presentation in a CACA workshop at Pittcon 2016. An honorarium and travel expenses are included with the award.


The CACA Young Investigator Award is open to all CACA members who are within 10 years of receiving their highest degree at the time of the award session.

* To register as a member by joining the CACA group on LinkedIn: http://www.linkedin.com/groups?gid=1857030. There is no membership fee.


Application packages will be evaluated by the CACA Awards committee. The applicants are judged on the originality and overall quality of work, significance to the advancement of separation science and other supporting factors. Measures of the impact of the work include publications, presentations, patents, and leadership roles at their research fields or place of business.

Application package:

An application package must consist of the following items,

1) A cover letter summarizing the applicant’s contribution to the field of separation science.
2) A resume including contact information, academic credentials, work experience, and publication list of the nominee.
3) A maximum of three supporting letters from individuals in the field.
4) A headshot photo.

The candidates can be self-nominated or nominated by any separation science experts in the field. The deadline for the 2016 CACA Award nomination is Dec. 31, 2015. The awardee will be selected by the CACA Awards committee and notified by Jan. 31, 2016. Details of CACA and its free membership are listed at http://www.ca-ca.org/.

Please send the nomination materials electronically (single PDF file is preferred) to: This email address is being protected from spambots. You need JavaScript enabled to view it..


The 40th International Symposium on Capillary Chromatography (ISCC), the premier meeting for pressure and electrodriven microcolumn separations and related techniques, will be held May 29 - June 03, 2016 in the Congress Centre, Riva del Garda, Italy.

The program will include plenary lectures, keynote lectures by young scientists, prominently featured poster presentations, an instrument exhibition displaying the latest instrumental innovations, and a highly attractive social program offering opportunities to meet with world-renown scientists.

The 13th GCxGC Symposium will be organized jointly with the ISCC meeting to allow scientists to attend both meetings. The symposium will start with a short course on Sunday May 29 covering the fundamentals and applications of comprehensive GCxGC and with a plenary session on Monday May 30. Key-note lectures and posters will be included in the program of the ISCC meeting.

This year particular emphasis will be directed to combinations of capillary chromatography and 2D GC with various forms of MS from unit-mass to high resolution, and from single to hybrid analyzers.

Researchers in all areas relevant to the subjects of the symposia, are invited to submit abstracts. As traditional for the Riva meetings, the majority of presentations will be in poster format and the scientific committee will select contributions for oral presentation.

Exhibitors and sponsors are encouraged to participate by reserving booth space, and becoming a sponsor.

Please keep visiting our web site for new information as it becomes available.

Looking forward to meeting you in Riva del Garda,

Prof. L. Mondello

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Maximizing Resolution and Selectivity the Easy Way - Superficially Porous Column Chromatography

Join us for a webinar on Oct 29, 2015 at 9:30 AM EDT.

Register now!

Agilent webinarSuperficially porous particles offer improved efficiency and performance over similarly sized traditional totally porous particles. Higher efficiency leads to improved resolution and possible time savings with superficially porous particles, hence their popularity for HPLC analyses. Columns using superficially porous particles are available in a wide variety of particle sizes and stationary phase chemistries. This webinar will go into detail on how a chromatographer can exploit new phase chemistries on superficially porous columns, as well as utilize new chemistries optimized for long life at elevated pH for improved resolution.

What will you learn?

  • How to use the different superficially porous phase chemistries to expedite high resolution and high selectivity method development
  • How to use pH to manipulate selectivity of ionizable compounds
  • How to choose a superficially porous particle column that best suits your laboratory setup

After registering, you will receive a confirmation email containing information about joining the webinar.

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