Speaker: Yichen Wang, Specialist of Ion Chromatography, Product Manager of SHINE Ion Chromatography
Yichen Wang
When: Wed, Aug 25, 2021 9:00 AM - 10:00 AM PDT
Abstract: Ion chromatography (IC), a well-established form of liquid chromatography, uses ion-exchange resins to separate cations or anions. There are two types of IC, anion-exchange and cation-exchange. Equipped with different detectors, IC could be a powerful separation technique to address challenging analytical tasks. For example, IC can detect carbohydrate in dairy products using electrochemical detector. Recently, IC has been extensively used for purification and characterization of biopharmaceutical drugs such as monoclonal antibody (mAb) and adeno-associated virus (AAV). Trace analysis of elemental impurities with low detection limit can be achieved with combination of ICP-MS/MS. It is possible to detect hexavalent ions such as chromium at ppt levels in toys.
Due to its excellent sensitivity, selectivity, and fast speed, IC has proven to be a very useful technique for determination of both organic and inorganic ions (in particular non-metal ions) and applied in various fields such as food, environmental, material and pharmaceutical analyses. To explore the growing interest of IC in pharmaceutical industry, this seminar will start with a brief introduction of IC principle, operation, and instrumentation followed by its application in analysis of raw materials, intermediates, drug substance, excipients, and finished drug products based on pharmacopeia standards from different countries.
Key Learning Objectives:
• Brief introduction of IC Principle, operation and instrumentation
• Application of IC in pharmaceutical drug analysis
Who Should Attend:
• IC users and method developers in pharmaceutical, chemical, clinical, environmental, agrichemical, contract research organizations, universities, and governmental laboratories.